28.01.2013

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Announcements / Press Releases

Global leaders in Davos promote accountability & transparency in advancing progress against malaria and other global health challenges [RBM] — (English)
The Roll Back Malaria Partnership (RBM) and the Center for Global Health & Diplomacy (GHD) co-hosted a reception and dinner in the margins of the World Economic Forum in Davos to highlight the importance of accountability and transparency to advance global health progress. HE Mr. Jakaya Kikwete, President of the United Republic of Tanzania, HRH Princess Astrid of Belgium and RBM Special Representative, together with Prof. Jeffrey Sachs, UN Secretary-General’s Special Advisor on MDGs made keynote remarks. Guests included the Honorable Ministers of Health of Senegal and Nigeria, Honorable Minister of the Cabinet Office of the United Kingdom, Secretary-General of the UN International Telecommunication Union, and Executive Director of UNFPA, alongside distinguished participants from governments, businesses, NGOs, the UN and international global health community...

RBM’s Princess Astrid of Belgium and FIFA President share views on vital link between football and malaria control [RBM] — (English)
HRH Princess Astrid of Belgium, Special Representative of the Roll Back Malaria Partnership (RBM), met with FIFA President Mr. Joseph Blatter and Secretary-General Mr. Jerome Valcke at FIFA headquarters to thank FIFA for lending its support to the fight against malaria...

132nd WHO Executive Board session [WHO] — (English)
Documentation and key issues...

Germany Makes EUR 1 Billion Contribution to the Global Fund [The Global Fund News release] — (English)
The Federal Republic of Germany announced today that it will contribute EUR 1 billion to the Global Fund to Fight AIDS, Tuberculosis and Malaria, enabling health workers to continue efforts to prevent and treat these three highly infectious diseases...

Global Fund Executive Director Calls for Focused Action to Fight Infectious diseases [The Global Fund News release] — (English)
Mark Dybul, Executive Director of the Global Fund to Fight AIDS, Tuberculosis and Malaria said today that concentrated action will achieve significantly greater impact on infectious diseases that threaten maternal and child health...

DRC: Thousands risk violence and malaria in Katanga [MSF News Release] — (English)
As tensions increase between government forces and Mai-Mai militias in the Katanga province of the Democratic Republic of Congo (DRC), Médecins Sans Frontières/Doctors Without Borders (MSF) calls on all parties to avoid harming civilians who have fled in their thousands into the surrounding bush...

National Health Systems Face Fundamental Transformations [WEF Press Release] — (English)
The World Economic Forum published a report on Sustainable Health Systems today, identifying how health systems of the future could be shaped. The report, prepared in cooperation with McKinsey & Company, is based on the assumption that health systems need to change fundamentally to become more sustainable. It contains three major parts: five country studies, three major strategic themes towards sustainable health systems and three contextual scenarios for 2040...

Beautiful and Colorful Striped Long Lasting Mosquito Bed Nets Are Now Available in Kigali, in Zambia and in Uganda [Bestnet Press Releases] — (English)
Now, in addition to being available in traditional white, Netprotect® bed nets are available in decorative yellow and blue stripes: in Kigali, in Zambia, and in Uganda...

Updates from RBM Harmonization Working Group [RBM HWG] — (English)
Thirteenth HWG Meeting Summary, HWG Resource Mobilization Workstream Teleconference: 24 January 2013, HWG Teleconference: 18 January 2013, RBM Harmonization Working Group Official Membership as of 28 January 2013...

2012 CARN Coordination Committee meeting report [RBM CARN] — (English)
Now available in English and French...

WHO/GMP: Consultant [WHO/GMP] — (English)
GMP is currently looking for a consultant to manage a consultative and inclusive process of developing a plan for the control and elimination of P. vivax which will form an integral part of the Global Technical Strategy for Malaria Control & Elimination, 2016-2025...

MMV: Human Resources Officer [MMV] — (English)
Application deadline: 10 February 2013...

fhi360: Senior Technical Advisor, Malaria [fhi360] — (English)
FHI 360 is looking for candidates for an important position, Senior Technical Advisor, Malaria in the Integrated Health Sciences Department within the Global Health, Population & Nutrition Group. FHI 360 is looking for an accomplished expert in the field of malaria to help lead the development of a malaria portfolio in support of FHI 360’s strategic plan....

B&M Gates Foundation: Deputy Director, Malaria [BMGF] — (English)
Requisition Number 3719BR...

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Articles requiring subscription or registration

Slow parasite clearance rates in response to artemether in patients with severe malaria [The Lancet Infectious Diseases, Volume 13, Issue 2, Pages 113 - 114, February 2013] — (English)
We recently reported artemisinin-resistant, uncomplicated Plasmodium falciparum malaria in Pursat, western Cambodia...

Synergies in integrated malaria control [The Lancet Infectious Diseases, Vol. 13 No. 2 p 112] — (English)
Combination of malaria vector control strategies, particularly insecticide-based approaches, needs careful consideration. Responsibility to implement a sound strategy goes beyond immediate alleviation of disease burden, to deceleration of the diminishing returns of future control efforts resulting from the spread of insecticide resistance. Vincent Corbel and coauthors1 present a clustered randomised trial examining the combined efficacy of pyrethroid-impregnated bednets with either indoor residual spray (IRS) with carbamates, or a carbamate-impregnated plastic sheeting placed high up on household walls...

Synergies in integrated malaria control – Authors' reply [The Lancet Infectious Diseases, Vol. 13 No. 2 pp 112-113] — (English)
We agree with Laith Yakob and coauthors that promotion of complementary methods by which to reduce vectorial capacity of mosquitoes and hence to effectively tackle malaria transmission is needed. However, we consider some of their statements explaining the absence of synergism between long-lasting insecticidal mosquito nets (LLIN) and indoor residual spraying (IRS) in our clinical trial1 to be inaccurate. In our study, malaria incidence was estimated in all children younger than 6 years in the 28 villages (ie, a cohort of 1700 children) and the vector control interventions were not restricted to a subpopulation, except in the reference group that received selective coverage of LLIN (ie, pregnant women and children <6 years), in agreement with the policy of the Malaria Control Programme (MCP) in 2007...

MRI Findings in a Cohort of Brain Injured Survivors of Pediatric Cerebral Malaria [Am J Trop Med Hyg.] — (English)
A prospective cohort study of retinopathy-confirmed cerebral malaria (CM) survivors identified 42 of 132 with neurologic sequelae...

Germany donates €1bn to Global Fund to Fight Aids, Tuberculosis and Malaria [BMJ 2013; 346 doi: http://dx.doi.org/10.1136/bmj.f566] — (English)
The philanthropist Bill Gates has welcomed a €1bn (£0.9bn; $1.3bn) donation to the Global Fund to Fight Aids, Tuberculosis and Malaria, saying that it would put the fund in a strong position when it asked for donations later in the year...

When they don't bite, we smell money: understanding malaria bednet misuse [Parasitology / FirstView Article, pp 1-7] — (English)
Here, we use a game theory mathematical model to understand the possible roles of poverty and malaria infection protection by individual and emerging ‘community effects’ on the ‘misuse’ of malaria bednets...

Cyclic patterns of cerebral malaria admissions in Papua New Guinea for the years 1987-1996 [Epidemiology and Infection] — (English)
This study aimed at confirming previous results on malaria cyclicity by exploring whether trans-year and/or multiannual cycles might exist. The exploration of underlying chronomes (time structures) was done with raw data (without smoothing) by linear and nonlinear parametric regression models, autocorrelation, spectral (Fourier) and periodogram regression analysis...

Antimalarial activities of medicinal plants and herbal formulations used in Thai traditional medicine [Parasitol Res. 2013 Jan 23] — (English)
The present study aimed to investigate antimalarial activities of a total of 27 medicinal plants and 5 herbal formulations used in Thai traditional medicine against chloroquine-resistant (K1) and chloroquine-sensitive (3D7) P. falciparum clones...

Identification of VAR2CSA Domain Specific Inhibitory Antibodies of the Plasmodium falciparum Erythrocyte Membrane Protein 1 using a novel Flow Cytometry Assay [CVI.00638-12] — (English)
In order to identify and develop recombinant proteins suitable for clinical development, DBL2X and DBL3X as well as their respective third subdomain (S3) from the FCR3 parasite clone were expressed in E. coli, refolded and purified...

Evaluation of the sensitivity of a pLDH-based and an aldolase-based Rapid Diagnostic Test for the diagnosis of uncomplicated and severe malaria caused by PCR-confirmed Plasmodium knowlesi, Plasmodium falciparum and Plasmodium vivax [JCM.03285-12] — (English)
The pLDH-based RDT was highly sensitive for the diagnosis of severe malaria from all species; however, neither the pLDH- or aldolase-based RDT demonstrated sufficiently high overall sensitivity for P. knowlesi. More sensitive RDTs are needed in knowlesi-endemic regions...

Malaria Prevention in Zambia: A Practical Application of the Diffusion of Innovations Model [J Transcult Nurs January 22, 2013 1043659612472061] — (English)
Transcultural nursing educators can be change agents for health issues in other cultures. Yet unfamiliar disease processes and the foreign environment provide challenges that must be overcome to achieve a lasting, effective, and positive change. Rogers’s Diffusion of Innovations Model can be used to plan and implement community-focused interventions into the cultures of developing nations, specifically malaria prevention in Zambia. Transcultural nurse educators could use concepts from the model to effect change in other cultures or communities...

Novel Type II Fatty Acid Biosynthesis (FAS II) Inhibitors as Multistage Antimalarial Agents [ChemMedChem. 2013 Jan 22. doi: 10.1002/cmdc.201200407] — (English)
Using virtual screening based on two crystal structures of PfENR, we identified a structurally novel class of FAS inhibitors. Subsequent chemical optimization yielded two compounds that are effective against multiple stages of the malaria parasite...