18.02.2018

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Announcements / Press Releases

Islamic Development Bank to expand malaria elimination efforts [RBM] — (English)
The President of the Islamic Development Bank (IDB), Dr Ahmad Mohamed Ali Al Madani, met with Dr Fatoumata Nafo-Traoré at the bank's headquarters in Jeddah, Saudi Arabia, this week to explore investment opportunities to eliminate malaria in selected countries of the Organization of Islamic Cooperation (OIC), the founding institution of the IDB. Dr Traoré was a guest of the IDB together with Professor Ogobara Doumbo, Director of the Malaria Research and Training Center at the University of Bamako, Mali....

"Invest in the Future: Defeat Malaria" [RBM] — (English)
World Malaria Day (April 25) is fast approaching. Each year, Roll Back Malaria (RBM) partners unite their advocacy efforts around a common World Malaria Day theme. As RBM zeros in on achieving the malaria MDG by 2015, partners have agreed on a 3-year theme to call attention to the big push needed in countries to end malaria: “Invest in the future. Defeat malaria.”...

« Investir dans l'avenir : vaincre le paludisme » [RBM] — (English)
La Journée mondiale de la lutte contre le paludisme (25 avril) approche à grands pas. Chaque année, les partenaires RBM unissent leurs efforts de plaidoyer autour du thème commun de la Journée mondiale de la lutte contre le paludisme. Alors que RBM s'efforce d'atteindre les OMD liés au paludisme d'ici 2015, les partenaires se sont mis d'accord sur un thème pour trois ans, afin d'attirer l'attention sur les efforts massifs (« the big push ») qui sont nécessaires pour éliminer le paludisme des pays touchés : « Investir dans l'avenir. Vaincre le paludisme » ...

Strengthening malaria diagnosis in Namibia: Reporting back on our investment [MNM UK] — (English)
We’ve been working with partners in Namibia to address a key challenge in the country’s efforts to eliminate malaria: consistent and effective diagnosis and treatment...

B&M Gates Foundation: Deputy Director, Malaria [BMGF] — (English)
Requisition Number 3719BR...

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Articles requiring subscription or registration

Malaria drug made in yeast causes market ferment [Nature 494, 160–161 (14 February 2013) doi:10.1038/494160a] — (English)
Synthetic biology delivers combination therapies into an uncertain market...

Bigger babies for women given extra prophylaxis against malaria [BMJ 2013; 346 doi: http://dx.doi.org/10.1136/bmj.f907] — (English)
Updated guidelines from the World Health Organization recommend boosting malaria prophylaxis for pregnant women in sub-Saharan Africa. The new policy could help increase average birth weights and reduce the number of babies born weighing less than 2500 g, according to a meta-analysis...

Comparison of routine prenatal iron prophylaxis and screening and treatment for anaemia: pregnancy results and preliminary birth results from a pragmatic randomised controlled trial (PROFEG) in Maputo, Mozambique. [BMJ Open. 2013 Feb 8;3(2). doi:pii: e001948. 10.1136/bmjopen-2012-001948. Print 2013] — (English)
To present the pregnancy results and interim birth results of a pragmatic randomised controlled trial comparing routine iron prophylaxis with screening and treatment for anaemia during pregnancy in a setting of endemic malaria and HIV...

Intermittent Preventive Therapy for Malaria During Pregnancy Using 2 vs 3 or More Doses of Sulfadoxine-Pyrimethamine and Risk of Low Birth Weight in Africa [JAMA. 2013;309(6):594-604. doi:10.1001/jama.2012.216231] — (English)
Systematic Review and Meta-analysis...

Elevated Levels of High-Mobility Group Box-1 (HMGB1) in Patients with Severe or Uncomplicated Plasmodium falciparum Malaria [Am J Trop Med Hyg 2013 12-0530] — (English)
Elevated HMGB1 in patients with ongoing Plasmodium falciparum infections might prolong inflammation and the febrile state of malaria and could offer a potential target for therapeutic intervention...

High Levels of Genetic Diversity of Plasmodium falciparum Populations in Papua New Guinea despite Variable Infection Prevalence [Am J Trop Med Hyg 2013 12-0056] — (English)
Here, we investigate the relationship between local variation in malaria epidemiology and parasite genetic diversity in Papua New Guinea (PNG)...

Systematic Review and Meta-analysis [Clin Infect Dis. (2013) doi: 10.1093/cid/cit068] — (English)
The main outcome was clinical treatment failure rate following treatment with artemether/lumefantrine (AL)...

‘Big data’ from shrinking pathogen populations [Molecular Ecology, Volume 22, Issue 2, pages 271–272] — (English)
In this issue of Molecular Ecology, Nkhoma et al. (2013) explore the applications of longitudinal genomic diversity data for detecting changes in the prevalence and transmission of the Plasmodium falciparum malaria parasite in South-East Asia...

Asymptomatic plasmodial infection is associated with increased TNFRII-expressing Tregs and suppressed type 2 immune responses [J Infect Dis. (2013) doi: 10.1093/infdis/jit058] — (English)
Malaria parasites associated with asymptomatic infections seem to result in increased TNFRII expression on Tregs as well as suppressed Th2 cytokine responses, features that might be important for survival of the parasites in asymptomatic carriers...

Use of the Rapid BinaxNOW Malaria Test in a 24-Hour Laboratory Associated with Accurate Detection and Decreased Malaria Testing Turnaround Times in a Non-Endemic, Pediatric Setting [doi: 10.1128/​JCM.00293-13] — (English)
The impact of implementing the BinaxNow malaria test (RDT) was evaluated. From 288 tests, 34 malaria cases were detected. Laboratory turnaround time decreased from 9.8 to 1.7 hours for report of any Plasmodium spp, 10.2 to 1.6 hours for P. falciparum and 8.6 to 1.1 hours for any result...

Genetic diversity of Plasmodium falciparum infections in mild and severe malaria of children from Kampala, Uganda [Parasitology Research February 2013] — (English)
The study included 164 children presenting with mild and severe malaria from central Uganda where malaria is meso-endemic...

A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970–2010 [J. R. Soc. Interface 6 April 2013 vol. 10 no. 81 20120921] — (English)
To assess how theory has changed to confront evolving public health challenges, we compiled a bibliography of 325 publications from 1970 through 2010 that included at least one mathematical model of mosquito-borne pathogen transmission and then used a 79-part questionnaire to classify each of 388 associated models according to its biological assumptions...

Monitoring of Arsenic Levels in Some Ready-to-Use Anti-Malaria Herbal Products from Drug Sales Outlets in the Madina Area of Accra, Ghana [Food and Chemical Toxicology] — (English)
In this study, four common aqueous based anti-malaria herbal products (coded HEB, KFE, MDM and NIB) which are used by Ghanaian population from pharmacy/herbal stores in the Madina area, Accra were blindly and randomly sampled for cadmium (Cd), arsenic (As) and Lead (Pb) analysis using Atomic Absorption Spectrophotometry technique...

Management of Uncomplicated Malaria in Underfives in Private and Public Health Facilities in South-Eastern Nigeria: A Clinical Audit of Current Practices [Malaria Research and Treatment Volume 2013 (2013), Article ID 575080, 6 pages http://dx.doi.org/10.1155/2013/575080] — (English)
The utilization of ACTs for treating uncomplicated malaria in the State has improved but clinical assessment of patients and laboratory confirmation of diagnosis are suboptimum...

Horizontal gene transfer of epigenetic machinery and evolution of parasitism in the malaria parasite Plasmodium falciparum and other apicomplexans [BMC Evolutionary Biology 2013, 13:37 doi:10.1186/1471-2148-13-37] — (English)
.In this work, we study SET-domain bearing genes that are implicated in mediating immune evasion, invasion and cytoadhesion pathways of modern apicomplexans, including malaria parasites..

Consistently high estimates for the proportion of human exposure to malaria vector populations occurring indoors in rural Africa [nt. J. Epidemiol. (2013) doi: 10.1093/ije/dys214] — (English)
nsecticide-treated nets (ITNs) and indoor residual spraying (IRS) are highly effective tools for controlling malaria transmission in Africa because the most important vectors, from the Anopheles gambiae complex and the A. funestus group, usually prefer biting humans indoors at night...

A systematic review of safety data reporting in clinical trials of vaccines against malaria, tuberculosis, and human immunodeficiency virus [Vaccine] — (English)
We performed a systematic review of publications describing the safety results from clinical trials of malaria, TB and HIV vaccines, to ascertain the nature and consistency of safety data collection and reporting...

Why do some African children develop severe malaria? [Parasitology Today Volume 7, Issue 10, 1991, Pages 277–281] — (English)
In this article, Brian Greenwood, Kevin Marsh and Robert Snow review some of those characteristics of the parasite and the host that may influence the outcome of a malaria infection. Identification of the relative importance of the many factors likely to be involved is needed in order to develop rational strategies for the prevention of deaths from malaria among children in malaria-endemic area...