18.03.2018

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Announcements / Press Releases

Ban tells public health educators to get involved in post-2015 development agenda [UN News Centre] — (English)
Secretary-General Ban Ki-moon has called on the global public health academic community to be active partners in the future development framework as the international community starts to set its post-2015 anti-poverty goals...

Understanding the New Funding Model [Friends of the Global Fund Africa] — (English)
Replacing the former rounds-based model, the new funding model approved in a series of decision points at Board Meetings was created to allow the Global Fund to invest more strategically, achieve greater impact, and engage implementers and partners more effectively...

Nigeria needs 'greater awareness' about malaria related maternal deaths [International Federation of Gynecology and Obstetricse] — (English)
Malaria is responsible for 11 per cent of maternal deaths in Nigeria, it has been claimed...

NetsforLife® Inspiration Fund exceeds goal to fight malaria [Episcopal Relief & Development -- Press Release] — (English)
The NetsforLife® Inspiration Fund has successfully exceeded its $5 million goal due to the incredible generosity of supporters across the Episcopal Church and beyond...

Ecuador: success in malaria control and community mobilization [The Global Fund blog] — (English)
Between 2000 and 2009, Ecuador has seen a reduction of 96% in the number of reported malaria cases associated with intense malaria program activity. Today, only 4% of the 13.8 million people who live in Ecuador are at high risk for malaria...

Peter Piot awarded Hideyo Noguchi Africa Prize [LSHTM News release] — (English)
The Director of the School, Professor Peter Piot, will be awarded the Hideyo Noguchi Africa Prize for Medical Research, the Government of Japan announced today...

Dr. Coutinho Wins Hideyo Noguchi prize 2013 [Makerere University News release] — (English)
Laureates of the Second Hideyo Noguchi Africa Prize...

ACT Consortium: Technical Communications Officer [ACT Consortium] — (English)
Application deadline: 22 March 2013...

B&M Gates Foundation: Deputy Director, Malaria [BMGF] — (English)
Requisition Number 3719BR...

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Articles requiring subscription or registration

Human Host-Derived Cytokines Associated with Plasmodium vivax Transmission from Acute Malaria Patients to Anopheles darlingi Mosquitoes in the Peruvian Amazon [Am J Trop Med Hyg 2013 12-0752] — (English)
This study tested the hypothesis that pro- or anti-inflammatory cytokines are associated with transmission of Plasmodium vivax to Anopheles darlingi mosquitoes in experimental infection...

Comparative evaluation of efficacy and safety of artesunate–lumefantrine vs. artemether–lumefantrine fixed-dose combination in the treatment of uncomplicated Plasmodium falciparum malaria [Tropical Medicine & International Health] — (English)
Artesunate (100 mg)/lumefantrine (480 mg) fixed-dose combination could add one more option to currently available artemisinin combinations in treatment of uncomplicated P. falciparum malaria...

Suppression of Host p53 Is Critical for Plasmodium Liver-Stage Infection [Cell Rep. 2013 Mar 5. pii: S2211-1247(13)00069-7. doi: 10.1016/j.celrep.2013.02.010] — (English)
Plasmodium parasites infect the liver and replicate inside hepatocytes before they invade erythrocytes and trigger clinical malaria. Analysis of host signaling pathways affected by liver-stage infection could provide critical insights into host–pathogen interactions and reveal targets for intervention. Using protein lysate microarrays, we found that Plasmodium yoelii rodent malaria parasites perturb hepatocyte regulatory pathways involved in cell survival, proliferation, and autophagy....

A Key Role for Lipoic Acid Synthesis During Plasmodium Liver stage Development [Cellular Microbiology] — (English)
This finding has implications for understanding Plasmodium pathogenesis in malnourished children that bear the brunt of malarial disease. This study also highlights the potential of exploiting lipid metabolism pathways for the design of genetically attenuated sporozoite vaccines...

Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family [Molecular Microbiology] — (English)
We present systematic gene deletion analyses of all eight Plasmodium rhomboid-like proteins as a means to discover stage-specific phenotypes and potential functions in the rodent malaria model, P. berghei...

Hide and seek: hematological aspects of malaria – a developing country perspective [JIDC doi:10.3855/jidc.2332] — (English)
We aimed to assess whether complete blood indices would increase the probability of malaria in patients with acute febrile illness...

Tuberculosis with malaria or HIV co-infection in a large hospital in Luanda, Angola [JIDC doi:10.3855/jidc.2703] — (English)
This study aimed to characterize all TB cases seen at the Hospital Sanatório de Luanda, and to determine the co-infection rate with HIV and/or malaria...

Low sensitivity of malaria rapid diagnostic tests stored at room temperature in the Brazilian Amazon Region [JIDC doi:10.3855/jidc.2564] — (English)
This study aimed to evaluate the performance of two rapid diagnostic tests (RDTs) targeting different malaria antigens stored at room temperature in the Brazilian Amazon Region...

A systematic review of the impact of malaria prevention in pregnancy on low birth weight and maternal anemia [International Journal of Gynecology & Obstetrics] — (English)
To evaluate the association between recommended preventative SP programs in pregnancy and low birth weight (LBW) and maternal anemia through available clinical trial, observational, and programmatic evaluation studies...

Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin [British Journal of Pharmacology DOI: 10.1111/bph.12156] — (English)
We explored the in vivo long-term effect of borrelidin and mupirocin treatments against lethal P. yoelii murine malaria...

An Intensive Longitudinal Cohort Study of Malian Children and Adults Reveals No Evidence of Acquired Immunity to Plasmodium falciparum Infection [Clin Infect Dis. (2013) doi: 10.1093/cid/cit174] — (English)
Despite years of exposure to intense P. falciparum transmission, there is no evidence of acquired, sterile immunity to P. falciparum infection in this population, even as clinical immunity to blood-stage malaria is clearly acquired. Understanding why repeated P. falciparum infections do not induce sterile protection may lead to insights for developing vaccines that target the liver stage in malaria-endemic populations...

Plasmodium falciparum synthetic LbL microparticle vaccine elicits protective neutralizing antibody and parasite-specific cellular immune responses [Vaccine] — (English)
This study demonstrates the potential of LbL particles as promising malaria vaccine candidates using the T1BT* epitopes from the P. falciparum CS protein...

Loop-mediated isothermal amplification test for the molecular diagnosis of malaria [Expert Review of Molecular Diagnostics 2013, Vol. 13, No. 2, Pages 205-218 , DOI 10.1586/erm.12.144] — (English)
This article summarizes current technical developments, applications, limitations and the future prospects for malaria diagnosis using LAMP in developed countries and endemic areas...