13.05.2018

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Announcements / Press Releases

15th Malaria in Pregnancy Working Group (MiPWG) meeting [MiP WG] — (English)
At the two-day annual meeting of the RBM Malaria in Pregnancy Working Group, RBM Partners will plan for an expanded coverage with interventions that specifically target malaria in pregnancy (MiP)...

Financement du Plan d’action global contre le paludisme (GMAP) [RBM] — (French)
Pourquoi investir dans la lutte contre le paludisme ? Tendances en matière de financement; Besoins de financement par région et par secteur; Sources de collecte de fonds et actions stratégiques...

Business leaders gather in Cape Town to promote the role of the private sector in fighting malaria in Africa [RBM] — (English)
The Roll Back Malaria Partnership, together with the Global Fund to Fight AIDS, Tuberculosis and Malaria, Friends Africa (and in cooperation with ONE) co-hosted a reception and corporate executive dinner in the margins of the World Economic Forum Africa in Cape Town to highlight the role of the private sector in advancing progress against malaria control in Africa...

Semisynthetic artemisinin achieves WHO prequalification [PATH press release] — (English)
First non-plant-derived source of a key ingredient in the top malaria drug will increase access to treatment...

Uganda Launches Largest Malaria Prevention Campaign [The Global Fund press release] — (English)
The Global Fund to Fight AIDS, Tuberculosis and Malaria announced today that it is supporting Uganda in the distribution of over 15.5 million long lasting insecticide-treated nets, making it the largest malaria prevention campaign this year...

Switzerland Raises Contribution to Global Fund by 43 Percent [The Global Fund press release] — (English)
The Global Fund to Fight AIDS, Tuberculosis and Malaria welcomed an announcement from Switzerland that it intends to increase its contribution to the Global Fund by 43 per cent in 2013...

TB, HIV and Malaria Vaccine Research [Aeras] — (English)
Aeras, a nonprofit biotech advancing TB vaccines for the world, the University of Oxford and Okairos, a biopharmaceutical company specializing in T-cell vaccines, today announced a $2.9 million grant to Aeras in support of a collaboration among the three parties to support the development of vaccines against tuberculosis, HIV and malaria...

Bacteria in mosquitoes could help stop spread of malaria [Johns Hopkins and Michigan State universities] — (English)
Scientists at Johns Hopkins and Michigan State universities have made a key discovery in the fight against malaria, one that could one day lead to the ability to control the disease with a specific bacterium, NPR reported...

The New York Academy of Sciences Partners to Host International Malaria Research Conference [The New York Academy of Sciences] — (English)
From May 28 – 29, 2013, researchers will gather in CosmoCaixa Barcelona (Spain), for the Advances in Plasmodium vivax Malaria Research conference, presented by the New York Academy of Sciences, the "la Caixa" Foundation, B-DEBATE, and the Barcelona Institute for Global Health (ISGlobal) and its research center, The Barcelona Centre for International Health Research (CRESIB)...

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Articles requiring subscription or registration

Wolbachia Invades Anopheles stephensi Populations and Induces Refractoriness to Plasmodium Infection [Science 10 May 2013: Vol. 340 no. 6133 pp. 748-751 DOI: 10.1126/science.1236192] — (English)
Wolbachia is a maternally transmitted symbiotic bacterium of insects that has been proposed as a potential agent for the control of insect-transmitted diseases. One of the major limitations preventing the development of Wolbachia for malaria control has been the inability to establish inherited infections of Wolbachia in anopheline mosquitoes. Here, we report the establishment of a stable Wolbachia infection in an important malaria vector, Anopheles stephensi. In A. stephensi, Wolbachia strain wAlbB displays both perfect maternal transmission and the ability to induce high levels of cytoplasmic incompatibility. Seeding of naturally uninfected A. stephensi populations with infected females repeatedly resulted in Wolbachia invasion of laboratory mosquito populations. Furthermore, wAlbB conferred resistance in the mosquito to the human malaria parasite Plasmodium falciparum...

The Human Malaria Parasite Pfs47 Gene Mediates Evasion of the Mosquito Immune System [Science DOI: 10.1126/science.1235264] — (English)
lasmodium falciparum transmission by Anopheles gambiae mosquitoes is remarkably efficient, resulting in a very high prevalence of human malaria infection in sub-Saharan Africa. A combination of genetic mapping, linkage group selection, and functional genomics was used to identify Pfs47 as a P. falciparum gene that allows the parasite to infect A. gambiae without activating the mosquito immune system. Disruption of Pfs47 greatly reduced parasite survival in the mosquito and this phenotype could be reverted by genetic complementation of the parasite or by disruption of the mosquito complement-like system. Pfs47 suppresses midgut nitration responses that are critical to activate the complement-like system. We provide direct experimental evidence that immune evasion mediated by Pfs47 is critical for efficient human malaria transmission by A. gambiae...

Transmission-blocking interventions eliminate malaria from laboratory populations [Nature Communications 4, Article number: 1812 doi:10.1038/ncomms2840] — (English)
Here we report the first experiments using a population, transmission-based study of Plasmodium berghei in Anopheles stephensi to assess the impact of a transmission-blocking drug upon both insect and host populations over multiple transmission cycles...

How can we determine the molecular clock of malaria parasites? [Trends in Parasitology, 10.1016/j.pt.2013.03.011] — (English)
This review addresses conflicting rate estimates of molecular evolution and suggests research directions to aid dating diversification events in malaria parasites...

Antimalarial potential of China 30 and Chelidonium 30 in combination therapy against lethal rodent malaria parasite: Plasmodium berghei [Journal of Complementary and Integrative Medicine. Volume 10, Issue 1, Pages 1–8, ISSN (Online) 1553-3840, ISSN (Print) 2194-6329, DOI: 10.1515/jcim-2012-0016] — (English)
The present study has been designed to evaluate the efficacy of Cinchona officinalis (Chin.) 30C and Chelidonium majus (Chel.) 30C in combination therapy against lethal murine malaria...