08.07.2013

Read this issue and previous issues online.

Follow us on:
Follow us on Twitter  Follow us on Facebook  Follow us on Flickr Follow us on YouTube   Follow us on LinkedIn

Announcements / Press Releases

Experts call for focus on social determinants to bolster malaria response [RBM / UNDP press release] — (English)
A global coalition of experts called this week for a broader response to malaria and expanded work to address the social and environmental factors that perpetuate it, saying the disease impedes efforts to tackle poverty and advance both economic and human development...

Global Fund Seeks Applicants for Technical Review Panel [Global Fund Announcement] — (English)
The Global Fund is seeking new members for a Technical Review Panel, an independent group of experts convened to assess the technical merit of funding requests to the Global Fund. The Panel also plays a role in guiding the strategic focus of Global Fund investments, by looking at effective program design and implementation strategies, so that the greatest impact can be achieved...

SARN Annual Constituencies Consultative meeting 2013 [RBM] — (English)
View SARN – RBM Partners Annual Constituencies Consultative Meeting Agenda...

Abuja +12 meeting [Abuja +12 ] — (English)
Visit the official Summit website...

Our leaders must keep the promise of Abuja [Reuters] — (English)
Source: Princess of Africa Foundation...

Technical Officer (Entomologist) [Swiss TPH] — (English)
Application deadline: 16 August 2013...

Technical Officer (Economist) [Swiss TPH] — (English)
Application deadline: 16 August 2013...

08.07.2013

{title} [{articlesource}] — ({language})
{description}...

07.07.2013

{title} [{articlesource}] — ({language})
{description}...

06.07.2013

{title} [{articlesource}] — ({language})
{description}...

05.07.2013

{title} [{articlesource}] — ({language})
{description}...

04.07.2013

{title} [{articlesource}] — ({language})
{description}...

03.07.2013

{title} [{articlesource}] — ({language})
{description}...

02.07.2013

{title} [{articlesource}] — ({language})
{description}...

Articles requiring subscription or registration

Weak Immune System? Malaria Doesn't Care [Science NOW] — (English)
Parasites have to walk a fine line. Be too weak, and they can't replicate or feed off you. Be too aggressive, and they risk killing you—their only home. That's what makes a new study, presented here last week at Evolution 2013, so surprising. Researchers have found that in mice with weak immune systems the malaria parasite becomes more aggressive, further compromising the health of an already compromised host. If the finding holds true in humans, it will help doctors understand why parasites might get more deadly over time...

Lasers Could Help Identify Malaria and Other Diseases Early [Science AAAS] — (English)
Combining lasers with a principle discovered by Alexander Graham Bell over 100 years ago, researchers have developed a new way to collect high-resolution information about the shape of red blood cells. Because diseases like malaria can alter the shape of the body's cells, the device may provide a way to accurately diagnose various blood disorders...

Malaria: Molecular secrets of a parasite [Nature (2013) doi:10.1038/nature12407] — (English)
Research shows how the malaria parasite Plasmodium falciparum manipulates the expression of its var genes to avoid recognition by the host immune system. Four experts comment on the implications of these results for our understanding of gene regulation in general and the development of antimalaria vaccines...

Malaria: Sensing when it's time for sex [Nature 499, 38–40 (04 July 2013) doi:10.1038/499038a] — (English)
Malaria parasites switch between developmental stages to facilitate their transmission to the mosquito vector. This switch seems to be initiated by parasite-to-parasite communication through membrane-bound vesicles...

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum [Nature (2013) doi:10.1038/nature12361] — (English)
These results uncover a previously unknown role of PfSETvs-dependent H3K36me3 in silencing var genes in P. falciparum that might provide a general mechanism by which orthologues of PfSETvs repress gene expression in other eukaryotes. PfSETvs knockout parasites expressing all PfEMP1 proteins may also be applied to the development of a malaria vaccine...

Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel [PNAS] — (English)
Our analysis shows that five of the nine mutations reduce AaNav1–1 sensitivity to pyrethroids...

Adult Malaria Chemoprophylaxis Prescribing Patterns in the Military Health System from 2007–2011 [Am J Trop Med Hyg 2013 13-0013] — (English)
The Military Health System (MHS), with 9.7 million beneficiaries, represents an enormous pool of potential travelers requiring malaria prevention measures. A systematic search of the MHS electronic pharmacy record was performed for prescriptions of atovaquone-proguanil (AP), chloroquine (CQ), doxycycline (DC), mefloquine (MQ), primaquine (PQ) to adult patients from 2007 through 2011...

Magnetic separation of malaria-infected red blood cells in various developmental stages [nal. Chem., Just Accepted Manuscript DOI: 10.1021/ac4012057] — (English)
The results showed excellent agreement with theoretically predicted values...

Plasmodium Nesting: Remaking the Erythrocytel from the Inside Out [Annual Review of Microbiology DOI: 10.1146/annurev-micro-092412-155730] — (English)
In this review, we discuss recent studies on erythrocyte remodeling, including mechanisms of protein export as well as the identity, functions, and subcellular locations of key exported proteins...

The Algal Past and Parasite Present of the Apicoplast [Annual Review of Microbiology DOI: 10.1146/annurev-micro-092412-155741] — (English)
We explore the cellular and molecular mechanisms that enabled a stable union of two previously independent organisms...