26.08.2013

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Announcements / Press Releases

Niger and Global Fund Sign €13.5 Million Malaria Grant [The Global Fund Announcement] — (English)
The Global Fund to Fight AIDS, Tuberculosis and Malaria has signed a 13.5 million euro grant agreement that will intensify efforts to provide families with mosquito nets and improve the diagnosis and treatment of malaria in Niger...

Niger: 180,000+ Children Benefit from New Approach to Malaria [Doctors Without Borders] — (English)
ach year, the arrival of the rainy season in Niger brings with it heightened risks of catching malaria from the mosquitoes that breed in stagnant water. To help prevent the spread of the disease, which can be fatal, Doctors Without Borders/Médecins Sans Frontières (MSF) carried out an initial round of seasonal malaria chemoprevention (SMC), a preventive method of care now recommended by the World Health Organization (WHO) that MSF employed previously in Chad and Mali...

Training module on malaria control: Entomology and vector control [WHO/GMP] — (English)
This Training module on malaria control: Entomology and vector control has been developed to improve the knowledge and skills of entomologists and vector control staff as well as of managers/senior health officers involved in malaria vector control at programme level...

Training module on malaria control: Case management [WHO/GMP] — (English)
This Training module on malaria control: Case management has been developed by WHO to improve the knowledge and skills of both health professionals involved in planning malaria case management as part of control and elimination programmes and clinicians managing malaria patients...

The Dominant Mosquito Vectors of Human Malaria in India [INTECH] — (English)
Anopheles mosquitoes - New insights into malaria vectors. New open access publication...

Consultancy positions under RETA 6321: Fighting HIV/AIDS, Malaria and Other Communicable Diseases in Asia and the Pacific [APLMA] — (English)
Application deadline: 11 September 2013...
APLMA Regional Executive Secretary
APLMA Regional Deputy Executive Secretary
APLMA Team Leader for Taskforce on Access to Quality Medicines and Other Technologies for Malaria in the Asia-Pacific
APLMA Team Leader for Task Force on Regional Financing
APLMA Team Leader for Champions’ Group
APLMA Administration and Finance Manager
APLMA Health Specialist
APLMA Knowledge Management Officer

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Articles requiring subscription or registration

Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent [SCIENTIFIC REPORTS] — (English)
Here, we present the X-ray crystallographic structures of FK506 binding domains (FKBDs) of PfFKBP35 and PvFKBP35 in complex with the newly identified inhibitor providing molecular insights into its mode of action...

Malaria and malnutrition: Niger's twin crises [The Lancet, Volume 382, Issue 9892, Pages 587 - 588, 17 August 2013 [Close] doi:10.1016/S0140-6736(13)61732-8] — (English)
The country's biggest killer is malaria. In 2012, more than 2·6 million cases of the disease were reported, alongside more than 3000 deaths. Its synergistic relationship with malnutrition prompted Médecins Sans Frontières (MSF) to issue Tackling the Deadly Combination of Malaria and Malnutrition earlier this year, a briefing document warning of the pending threat to Niger...

Malaria [The Lancet] — (English)
Enthusiasm for malaria elimination has resurfaced. This ambitious but laudable goal faces many challenges, including the worldwide economic downturn, difficulties in elimination of vivax malaria, development of pyrethroid resistance in some anopheline mosquitoes, and the emergence of artemisinin resistance in Plasmodium falciparum in southeast Asia. We review the epidemiology, clinical features, pathology, prevention, and treatment of malaria...

Evidence for genetic linkage between a polymorphism in the GNAS gene and malaria in South Indian population [Acta Tropica] — (English)
The complex imprinted GNAS locus which encodes G-alpha subunit (Gαs) is involved in a number of G-protein coupled signaling pathways in eukaryotic cell...

Is malarial anaemia homologous to neocytolysis after altitude acclimatisation? [International Journal for Parasitology] — (English)
We propose that Epo, which peaks during acute malaria and decreases after parasite clearance, could be contributing to anaemia causing neocytolysis during recovery from Plasmodium infection...

Dried blood spots in bioanalysis of antimalarials: relevance and challenges in quantitative assessment of antimalarial drugs [Bioanalysis September 2013, Vol. 5, No. 17, Pages 2171-2186 , DOI 10.4155/bio.13.180] — (English)
This review discusses the applicability and relevance of DBS in quantitative assessment of antimalarial drugs, the advantages and drawbacks of DBS, and the difficulties encountered during its implementation...

Malaria's Deadly Grip: Cytoadhesion of Plasmodium falciparum Infected Erythrocytes [Cellular Microbiology] — (English)
Here, we discuss recent findings on the origins and evolution of the var gene family, the structure-function of PfEMP1 proteins, and a distinct subset of PfEMP1 variants that have been associated with severe childhood malaria...

Plasmodium falciparum gametocytes: with a view to a kill [Parasitology, DOI: http://dx.doi.org/10.1017/S0031182013001236] — (English)
This review examines the gametocytocidal properties of currently available drugs as well as those in the development pipeline and examines the prospects for discovery of new anti-gametocyte compounds...