02.09.2013

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Announcements / Press Releases

Brazzaville to host 63rd session of WHO Regional Committee for Africa [WHO AFRO] — (English)
Health Ministers from the 47 countries in the WHO African Region will gather in Brazzaville, Congo, from 2 to 6 September 2013, to discuss a range of major health issues aimed at improving the health of people...

GMAP Financing in action [RBM] — (English)
August updates...

Malaria Policy Advisory Committee to convene for fourth meeting [WHO/GMP] — (English)
The fourth meeting of the Malaria Policy Advisory Committee (MPAC) will take place in Geneva, Switzerland, on 11-13 September. The MPAC will review evidence on intermittent preventive treatment in pregnancy (IPTp) and will discuss the findings of new expert reports on vector control interventions, drug resistance and containment, malaria burden estimation and other themes...

SMS FOR LIFE IMPROVING LIVES THROUGH MOBILE PHONES [MNM] — (English)
This is the second post in a series about mobile health, or mHealth -- a shorthand term for the practice of medicine and public health supported by mobile devices. We’ve dubbed similar efforts in the malaria space as mMalaria, and our Director of Research & Strategy Hannah Bowen is providing a deeper look into what mobile is doing to spur the malaria fight...

French Media Consultancy 2013/2014 [RBM] — (English)
Application deadline extended: 16 September 2013...

Medical Director (specialized in clinical pharmacology) [MMV] — (English)
Application deadline extended: 30 September 2013...

Consultancy positions under RETA 6321: Fighting HIV/AIDS, Malaria and Other Communicable Diseases in Asia and the Pacific [APLMA] — (English)
Application deadline: 11 September 2013...
APLMA Regional Executive Secretary
APLMA Regional Deputy Executive Secretary
APLMA Team Leader for Taskforce on Access to Quality Medicines and Other Technologies for Malaria in the Asia-Pacific
APLMA Team Leader for Task Force on Regional Financing
APLMA Team Leader for Champions’ Group
APLMA Administration and Finance Manager
APLMA Health Specialist
APLMA Knowledge Management Officer

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Articles requiring subscription or registration

Daily rhythms in antennal protein and olfactory sensitivity in the malaria mosquito Anopheles gambiae [Scientific Reports 3, Article number: 2494 doi:10.1038/srep02494] — (English)
Here we demonstrate that multiple rhythmically expressed genes including OBPs and takeout proteins, involved in regulating blood feeding behavior, have corresponding rhythmic protein levels as measured by quantitative proteomics...

A Modified Semi-Nested Multiplex Malaria PCR (SnM-PCR) for the Identification of the Five Human Plasmodium Species Occurring in Southeast Asia [Am J Trop Med Hyg 2013 13-0027] — (English)
We have modified an existing semi-nested multiplex polymerase chain reaction (PCR) by adding one Plasmodium knowlesi-specific nested PCR, and validated the latter against laboratory and clinical samples. This new method has the advantage of being relatively affordable in low resource settings while identifying the five human Plasmodium species with a three-step PCR...

Cost-Effectiveness Analysis of Introducing RDTs for Malaria Diagnosis as Compared to Microscopy and Presumptive Diagnosis in Central and Peripheral Public Health Facilities in Ghana [Am J Trop Med Hyg 2013 13-0033] — (English)
We developed incremental cost-effectiveness analyses with data from rural health facilities in Ghana with and without microscopy...

The Anopheles Innate Immune System in the Defense against Malaria Infection [J Innate Immun (DOI: 10.1159/000353602)] — (English)
This review will discuss our current understanding of the Anopheles mosquito's innate immune responses against the malaria parasite Plasmodium and the influence of the insect's intestinal microbiota on parasite infection...

EPIDEMIOLOGY OF PLASMODIUM RELICTUM INFECTION IN THE HOUSE SPARROW [Parasitology doi.org/10.1645/12-24.1] — (English)
Here, we investigated variability in prevalence and parasitemia of Plasmodium relictum in the house sparrow (Passer domesticus), across a large number of rural and urban populations (n = 16). We found that prevalence was not predicted by any of the host traits investigated...

Evaluation of substituted phenalenone analogues as antiplasmodial agents [Experimental Parasitology] — (English)
This is the first record of antiplasmodial activity on this type of scaffold, providing a new structural motif as a new lead for antimalarial activity...

Breadth of Anti-Merozoite Antibody Responses is Associated with the Genetic Diversity of Asymptomatic Plasmodium falciparum Infections and Protection against Clinical Malaria [Clin Infect Dis. (2013) doi: 10.1093/cid/cit556] — (English)
We assessed the breadth of antibody responses to several vaccine candidate merozoite antigens in relation to the infecting parasite population and clinical immunity...

Vector movement underlies avian malaria at upper elevation in Hawaii: implications for transmission of human malaria [Parasitol Res.] — (English)
An enhanced-mosquito-movement model from climate warming predicts increased transmission of malaria at upper elevation sites that are too cool for parasite development in the mosquito vector. We evaluate this model with avian malaria (Plasmodium relictum) at 1,900-m elevation on the Island of Hawaii, with air temperatures too low for sporogony in the vector (Culex quinquefasciatus)...

Short-Lived Effector CD8 T Cells Induced by Genetically-Attenuated Malaria Parasite Vaccination Express CD11c [IAI.00871-13] — (English)
The results suggest that CD11c marks a subset of highly inflammatory, short-lived antigen-specific effector cells, which may play an important role in eliminating infected hepatocytes...

Transdermal glyceryl trinitrate as an effective adjunctive treatment with artemether for late stage experimental cerebral malaria [AAC.00488-1] — (English)
In this study, we evaluated the effects of transdermal glyceryl trinitrate in preventing ECM and, in combination with artemether, rescuing late-stage ECM mice from mortality...

Plasmodium vivax malaria vaccines: Why are we where we are? [Human vaccines and immunotherapeutics] — (English)
While clinical trials of vaccines against P. falciparum are making fast progress, a very different picture is seen with P. vivax, where only few candidates are currently active in clinical trials...

A new hypothesis on the manifestation of cerebral malaria: The secret is in the live [Medical Hypotheses] — (English)
We believe our hypothesis better explains the pathogenesis of CM, does not have problems to deal with the exception data not explained by the previous hypotheses, and reveals new targets for adjunctive therapy...