30.09.2013

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Announcements / Press Releases

RBM Partnership welcomes UK's £I billion commitment and calls for full replenishment of the Global Fund [RBM] — (English)
This week, as global leaders gathered in New York for the United Nations General Assembly, the UK pledged a further £1 billion (US$1.6 billion) to the Global Fund over the next 3 years (2014-16)...

Le partenariat RBM applaudit l'engagement d'apport de 1 milliard de livres sterling du Royaume-Uni et appelle à une reconstitution complète des ressources du Fonds Mondial [RBM] — (English)
Cette semaine, alors que les dirigeants mondiaux étaient réunis à New York pour l'Assemblée générale des Nations Unies, le Royaume-Uni s'est engagé à apporter une contribution de 1 milliard de livres sterling (1,6 milliard de dollars) supplémentaire au Fonds Mondial au cours des trois prochaines années (2014-2016)...

UK Commits £1 Billion to the Global Fund [Global Fund press release] — (English)
The Global Fund to Fight AIDS, Tuberculosis and Malaria today congratulated the United Kingdom for demonstrating strong leadership in global health with a major contribution to the Global Fund for the next three years...

Strong Leadership by the UK Inspires Us All [Blog by Mark Dybul, Executive Director of the Global Fund to Fight AIDS, Tuberculosis and Malaria] — (English)
Leadership means taking bold action. The United Kingdom showed extraordinary leadership in global health this week by announcing an unequivocal commitment to fighting three of the world's most infectious diseases. People affected by HIV, tuberculosis and malaria in communities across our planet can rejoice in the knowledge that many more people will be able to live normal lives thanks to the support of the UK and other partners in our collective effort...

Multisectoral Action Framework for Malaria launched alongside 68th United Nations General Assembly [RBM / UNDP] — (English)
World leaders call for greater coordination among different sectors to combat malaria. More info on Multisectoral Action Framework for Malaria...

Multi-level strategy to fight malaria launched by UN development arm and partners [UN News centre] — (English)
The United Nations and a coalition of partners today launched a comprehensive approach to fighting malaria, a disease which – despite tremendous advances – still kills an estimated 660,000 people each year and poses a major challenge to development...

RBM's United Against Malaria Campaign selected as Social Cause of Soccerex Africa Forum [RBM] — (English)
The Roll Back Malaria Partnership will join leaders from the football industry at the Soccerex Africa Forum in Durban (1-2 October) to highlight the power of football in the fight against malaria...

Leaders in margins of the UN General Assembly celebrate successes and call for increased commitment and resources for malaria control [RBM] — (English)
More than 200 partners and guests gathered on the eve of the 68th United Nations General to reflect on the remarkable progress made in malaria control and recommit to accelerate the fight against the killer disease to meet the 2015 MDG deadline...

DOD Mefloquine Policy Mirrors FDA Update on Malaria Drug [American Forces Press Service] — (English)
The Defense Department's policy on the antimalarial drug mefloquine, which has been in use for decades, is consistent with a stronger, updated warning about the drug from the Food and Drug Administration, senior DOD officials said...

Joint Statement on accelerating efforts to achieve the health MDGs [WHO, UNFPA, UNAIDS, UNICEF and the UN Secretary General's Special Envoy for Financing the Health MDGs] — (English)
Joint Statement by WHO, UNFPA, UNAIDS, UNICEF and the UN Secretary General's Special Envoy for Financing the Health MDGs and for malaria on the occasion of the 68th General Assembly of the United Nations...

UNICEF and its partners respond to a resurgence of malaria cases in Chad [UNICEF press release] — (English)
In response to a resurgence of suspected cases of malaria in several parts of Chad , UNICEF in collaboration with WHO, is implementing an integrated response to support efforts already made by the Government in areas where the resurgence is highest...

Administrative Assistant, Business Development [MMV] — (English)
Application deadline: 6 October 2013...

Medical Entomology Officer [MCDI] — (English)
Location: Malabo, Equatorial Guinea ...

Monitoring and Evaluation Officer [MCDI] — (English)
Bioko Island Malaria Control Project, Phase III ...

Malaria Case Management Officer [MCDI] — (English)
Bioko Island Malaria Control Project, Phase III ...

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Articles requiring subscription or registration

Metabolic Profiling Framework for Discovery of Candidate Diagnostic Markers of Malaria [Nature.com Scientific Reports 3, Article number: 2769 doi:10.1038/srep02769] — (English)
We develop an analytical pipeline for characterizing Plasmodium infection in a mouse model and identify candidate urinary biomarkers that may present alternatives to immune-based diagnostic tools...

Malaria in pregnancy: increasing access and improving delivery of interventions [The Lancet Infectious Diseases, doi:10.1016/S1473-3099(13)70265-2] — (English)
The report by Anna Maria van Eijk and colleagues 1 in The Lancet Infectious Diseases into coverage of interventions for malaria in pregnancy highlights the achievements and continuing challenges of global malaria control overall...

Malaria Diagnostics in Clinical Trials [Am J Trop Med Hyg 2013 12-0675] — (English)
This report provides recommendations regarding quality management to ensure reproducibility across sites in clinical trials...

Mapping Malaria Transmission Intensity in Malawi, 2000–2010 [Am J Trop Med Hyg 2013 13-0028] — (English)
We assessed changes in transmission over this period of malaria control scale-up by compiling community Plasmodium falciparum rate (PfPR) data during 2000–2011 and used model-based geostatistical methods to predict mean PfPR2–10 in 2000, 2005, and 2010...

Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes, Using a Luciferase-based High-Throughput Assay [AAC.00870-13] — (English)
We have developed a luciferase-based high-throughput screening (HTS) assay using tightly synchronous stage I – III gametocytes from a recombinant P. falciparum line expressing GFP-luciferase...

Accessible Mutational Trajectories for the Evolution of Pyrimethamine Resistance in the Malaria Parasite Plasmodium vivax [Journal of Molecular Evolution] — (English)
We present evidence from one such species, Plasmodium vivax, which has experienced sustained selection for pyrimethamine resistance at the dihydrofolate reductase (DHFR) locus since the 1970s...

Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors of Plasmodium falciparum Enoyl-ACP-reductase (PfFabI) [J. Med. Chem. sACS Med. Chem. Lett.] — (English)
In this paper, new coumarin-based triclosan analogues are reported and their biological profile is explored in terms of inhibitory potency against enzymes of the PfFAS-II pathway...

Geographic population structure of the African malaria vector Anopheles gambiae suggests a role for the forest-savannah biome transition as a barrier to gene flow [Evol Appl. 2013 September; 6(6): 910–924.] — (English)
This analysis detected the presence of additional population structuring, with the M-form being subdivided into distinct west, central, and southern African genetic clusters...

Malaria vaccines: past, present and future [Arch Dis Child doi:10.1136/archdischild-2013-304173] — (English)
Despite the many challenges, efforts continue to design and evaluate malaria vaccine candidates. These candidates target different stages in the life cycle of Plasmodia. The most advanced vaccine candidates target the pre-erythrocytic stages in the life cycle of the parasite and include RTS,S/AS01, which has progressed through clinical development to the stage that it may be licensed in 2015...