7.04.2014

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Announcements / Press Releases

World Health Day 2014: small bite, big threat [WHO] — (English)
Mosquitoes, flies, ticks and bugs may be a threat to your health – and that of your family - at home and when travelling. This is the message of this year’s World Health Day, on 7 April. This short video highlights simple measures we can take to protect ourselves...

African Leaders & United Nations Secretary-General Highlight Malaria as Exemplary Investment for Development alongside EU-Africa Summit [RBM] — (English)
African leaders and Heads of State highlighted the importance of health for Africa’s development while gathering for the 4th EU-Africa Summit in Brussels just days before World Health Day (7 April). During a side-event hosted by the African Union Commission (AUC) and the Roll Back Malaria Partnership (RBM) speakers, including United Nations Secretary-General Ban Ki-moon, H.E. Dr Nkosazana Dlamini Zuma, Chairperson of the African Union Commission, Dr Fatoumata Nafo-Traore, RBM Executive Director, and Presidents of Liberia, Mozambique, the United Republic of Tanzania, Comoros and Ghana, among others, called for health to remain prominent on the development agenda to meet the 2015 deadline of the United Nations Millennium Development Goals (MDGs) and for the foreseeable future...

Partners in Eastern and Southern Africa Look at Investment Framework [The Global Fund] — (English)
Partners from countries in Eastern and Southern Africa opened a four-day meeting in the Namibian capital this week to examine how to make investments achieve the greatest possible impact in partnership with the Global Fund to Fight AIDS, Tuberculosis and Malaria...

Kenya Aims to Reduce Malaria Mortality by Two Thirds by 2017 [The Global Fund] — (English)
The Global Fund, the Government of Kenya, and the African Medical and Research Foundation today signed a grant agreement worth US$80 million that will support Kenya’s continuing fight against malaria...

Global Fund Taps Pharmaceutical Expertise in China [The Global Fund] — (English)
The Global Fund is deepening its partnership with China by tapping the expertise of Chinese pharmaceutical companies to develop and market drugs that will help defeat AIDS, tuberculosis and malaria all over the world...

Wellcome Trust welcomes UK funding bodies' open access policy [WellcomeTrust] — (English)
The Wellcome Trust welcomes the policy statement from HEFCE and the other three UK higher education funding bodies that requires research outputs (journal articles and conference proceedings) arising from their funding to be made open access in order to be eligible for submission to the post-2014 Research Excellence Framework...

World Health Day 2014: small bite, big threat [WHO EMRO] — (English)
The aim of World Health Day 2014 is to raise awareness of the problem of vector-borne diseases and encourage individuals and communities to take action to protect themselves against the vectors that cause disease. Vectors are organisms that transmit pathogens and parasites from one infected person (or animal) to another, putting health at risk, at home and during travels...

Sanaria® PfSPZ Malaria Vaccine Wins 2014 Vaccine Industry Excellence Award for “Best Prophylactic Vaccine” [Sanaria press release] — (English)
Sanaria received the 2014 Vaccine Industry Excellence Award for the “Best Prophylactic Vaccine” at a ceremony held March 25 in Washington DC during the 14th World Vaccine Congress. Vaccines from Sanofi Pasteur, GSK, and Novartis were among the 6 finalists competing with Sanaria. The awardee, Sanaria® PfSPZ Vaccine, demonstrated complete protection against malaria in all volunteers (6/6) who received high dose simmunizations in a trial at the Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), NIH...

Nothing But Nets Announces “Compete to Beat Malaria” Sports Challenge to Observe World Malaria Day [NothingButNets] — (English)
The United Nations Foundation’s Nothing But Nets campaign launched a nationwide challenge to ask Americans to “Compete to Beat Malaria.” The month-long campaign aims to send 25,000 insecticide-treated bed nets to families in sub-Saharan Africa...

Ninth annual meeting of the Vector Control Working Group [RBM VCWG] — (English)
Latest documents and presentations now available on the RBM web...

AMP Conference Call Minutes [AMP] — (English)
The AMP partnership conducts a weekly conference call on Wednesday at 10:00 EST. All members of the partnership are encouraged to participate in the weekly conference call via a toll free number. The call focuses on monitoring country progress, identifying bottlenecks, organizing technical support at both country level and remote (via e-mail, conference call), and sharing better practice...

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Articles requiring subscription or registration

Drug Combination Effective Against Malaria in Mice [JAMA. 2014;311(13):1282. doi:10.1001/jama.2014.3433] — (English)
A team of Canadian scientists reasoned that because both the malaria parasite and the host immune response to infection play roles in the development of malaria, adjunctive therapies that act on the host response may provide additional benefits to antiparasitic therapy. They found that compared with antimalarial therapy alone, adjunctive therapy with rosiglitazone—which has anti-inflammatory, antioxidant, and possible neuroprotective properties—was associated with reduced endothelial activation and enhanced expression of antioxidant enzymes and neuroprotective factors in the brains of infected mice...

An 11-year-old boy with Plasmodium falciparum malaria and dengue co-infection [BMJ Case Reports 2014; doi:10.1136/bcr-2013-202998] — (English)
The authors report a malaria and dengue co-infection in an 11-year-old boy who presented with sustained fever for 10 days...

Assessing the Performance of CareStart Malaria Pf/Pv Combo Test Against Thick Blood Film in the Diagnosis of Malaria in Northwest Ethiopia [Am J Trop Med Hyg 2014 13-0607] — (English)
A cross-sectional study was conducted to evaluate the performance of CareStart against thick blood smears among 398 acute febrile patients visiting the Felegeselam Health Center in December of 2011...

nfectious diseases related aeromedical evacuation of French soldiers in a level 4 military treatment facility: A ten year retrospective analysis [Travel Med Infect Dis.] — (English)
Infectious diseases were a rare of cause of medevac. Most of them were preventable. Lethal etiologies were represented by malaria and cerebro-meningeal infections...

Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates [Cellular and Molecular Life Sciences] — (English)
Understanding the targets and mechanisms of human immunity to malaria caused by Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for measuring immunity and exposure in populations...

Hemoglobinopathic erythrocytes affect the intraerythrocytic multiplication of Plasmodium falciparum in vitro [J Infect Dis. (2014) doi: 10.1093/infdis/jiu203] — (English)
We hypothesized that hemoglobinopathic erythrocytes reduce the intraerythrocytic multiplication of P. falciparum, potentially delaying the development of life threatening parasite densities until parasite clearing immunity is achieved...

Pharmacokinetic interactions between primaquine and chloroquine [AAC.02794-13] — (English)
This pharmacokinetic interaction may explain previous observations of synergy in preventing P.vivax relapse...

Functional antibodies against VAR2CSA in non-pregnant populations from Colombia exposed to Plasmodium falciparum and Plasmodium vivax [IAI.01594-14] — (English)
These findings may hold significant clinical relevance to the pathophysiology and outcome of malaria infections in this region...

In vivo splenic clearance corresponds with in vitro deformability of red blood cells from Plasmodium yoelii infected mice [10.1128/IAI.01525-13] — (English)
These results have clear implications for the mechanism of human malarial anemia, a severe pathological condition affecting malaria patients...