12.05.2014

Read this issue and previous issues online.

Follow us on:
Follow us on Twitter  Follow us on Facebook  Follow us on Flickr Follow us on YouTube   Follow us on LinkedIn

Announcements / Press Releases

RBM's Communication Community of Practice meets in Geneva [RBM] — (English)
Communication experts and practitioners from diverse RBM partner organisations came together to discuss how to best use social and behaviour change communication (SBCC) to strengthen malaria prevention, diagnosis and treatment...

15th Meeting of the RBM Harmonization Working Group [RBM] — (English)
RBM's Harmonization Working Group meets on 12-13 May to discuss the technical support it provides to endemic countries applying for funding through the Global Fund's New Funding Model...

RBM and the Global Fund train endemic countries to better manage supply and distribution of health commodities [RBM, The Global Fund] — (English)
National technical experts from Haiti, Yemen and 49 Sub-Saharan African countries have begun developing action plans to improve national logistics and management information systems (LMIS) at a three-day workshop, organised jointly by RBM and the Global Fund. A robust LMIS allows countries to avoid stock-outs and overstocking and ensure that the right health products are continuously available...

Frameworks for Results: tackling the international challenges of malaria and reproductive, maternal and newborn health [DFID] — (English)
An independent Mid Term Review of the Frameworks for Results is now published, along with DFID’s management response to the review...

Safety review of 8-aminoquinoline antimalarial medicines [WHO] — (English)
Written by external authors, this document reviews published and unpublished studies about the safety of primaquine and its precursors, with particular attention to haemolytic anaemia in G6PD-deficient individuals. In recent years, single-dose primaquine has received renewed attention because of its capacity to block human-to-vector transmission of malaria caused by P. falciparum. The study was prepared for and discussed at a 2012 meeting of the WHO evidence review group on the safety and effectiveness of single-dose primaquine as a P. falciparum gametocytocide...

New genomics technique could improve treatment and control of malaria [Wellcome Trust] — (English)
Single-cell genomics could provide new insight into the biology of malaria parasites (including their virulence and levels of drug resistance) to ultimately improve treatment and control of the disease, according to new research funded by the Wellcome Trust and the National Institutes of Health...

ExxonMobil, Its Employees and Retirees Give More than $1.3 Million to LSU Foundation [LSU press release] — (English)
ExxonMobil presented a check for $967,375.95 to the LSU Foundation as part of the ExxonMobil Foundation’s 2013 Educational Matching Gift Program...

Malaria Atlas Project: SEEG Data Archive Manager [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 05.06.2014...

Malaria Atlas Project: Postdoctoral Statistical Epidemiologist [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 21.05.2014...

Malaria Atlas Project: Research Assistant [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 21.05.2014...

Malaria Atlas Project: Senior Postdoctoral Modeller [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 21.05.2014...

Malaria Atlas Project: Senior Computational Statistician: Spatial Models [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 28.05.2014...

Bill & Melinda Gates Foundation: Senior Program Officer, Program Advocacy, Malaria Job [Gates Foundation] — (English)
Requisition Number 4763BR...

12.05.2014

{title} [{articlesource}] — ({language})
{description}...

11.05.2014

{title} [{articlesource}] — ({language})
{description}...

10.05.2014

{title} [{articlesource}] — ({language})
{description}...

9.05.2014

{title} [{articlesource}] — ({language})
{description}...

8.05.2014

{title} [{articlesource}] — ({language})
{description}...

7.05.2014

{title} [{articlesource}] — ({language})
{description}...

6.05.2014

{title} [{articlesource}] — ({language})
{description}...

Articles requiring subscription or registration

The rise and fall of malaria in a west African rural community, Dielmo, Senegal, from 1990 to 2012: a 22 year longitudinal study [The Lancet Infectious Diseases, doi:10.1016/S1473-3099(14)70712-1] — (English)
A better understanding of the effect of malaria control interventions on vector and parasite populations, acquired immunity, and burden of the disease is needed to guide strategies to eliminate malaria from highly endemic areas. We monitored and analysed the changes in malaria epidemiology in a village community in Senegal, west Africa, over 22 years...

Temporal Changes in Prevalence of Molecular Markers Mediating Antimalarial Drug Resistance in a High Malaria Transmission Setting in Uganda [Am J Trop Med Hyg 2014 13-0647] — (English)
We followed the prevalence of drug resistance-mediating P. falciparum polymorphisms in 982 samples from Tororo, a region of high transmission intensity, collected from three successive treatment trials conducted during 2003–2012, excluding samples with known recent prior treatment...

Hemoglobin Concentration and Parasitemia on Hospital Admission Predict Risk of Multiple Organ Dysfunction Syndrome among Adults with Malaria [Am J Trop Med Hyg 2014 13-0640] — (English)
We conducted a cohort study among 426 adult males admitted to hospital with malaria in Bogotá, Colombia. We estimated SOFA scores and relative risks (RRs) for MODS during hospitalization according to patients' characteristics on admission...

Decreasing malaria prevalence and its potential consequences for immunity in pregnant women [J Infect Dis. (2014) doi: 10.1093/infdis/jiu264] — (English)
The impact of falling parasite prevalence on anti-P. falciparum serological indicators in pregnant women varies by setting. Increased ITN coverage may affect development of antibodies to recombinant antigens, but levels of opsonising IgG remained stable over time. Opsonising IgG against placental-binding IEs may persist, thus offering longer-lasting protection against malaria during pregnancy...

Molecular and Microscopic-Based Characterization of Plasmodium spp. in Fars and Hormozgan Provinces, South of Iran [PMC] — (English)
Our results confirmed the considerable sensitivity of nested PCR for detection of the mixed infections...

How Malaria Parasites Get Turned On [Current biology] — (English)
The mechanisms underlying sexual stage switching in Plasmodium spp. have hitherto remained a mystery. However, two recent studies have revealed that an apicomplexan-specific DNA-binding protein is essential for the initiation of this cell fate decision, ultimately providing the malaria community with a novel and important tool in the battle to prevent malaria transmission...

New compounds hybrids 1H-1,2,3-triazole-quinoline against Plasmodium falciparum [GChemical Biology & Drug Design] — (English)
We synthesized 11 new quinoline-1H-1,2,3-triazole hybrids with different substituents in the 4-positions of the 1H-1,2,3-triazole ring, which were assayed against the W2-chloroquine-resistant P. falciparum clone...

Chemical composition and larvicidal activity of plant extracts from Clausena dentata (Willd) (Rutaceae) against dengue, malaria, and filariasis vectors [Parasitology Research May 2014] — (English)
Our result shows acetone leaf extracts of C. dentata have the potential to be used as an ideal eco-friendly approach for mosquito control...

A better resolution for integrating methods for monitoring Plasmodium falciparum resistance to antimalarial drugs [Acta Tropica] — (English)
Three main approaches are used to monitor antimalarial drug efficacy and drug resistance; namely, in vivo trials, in vitro/ex vivo assays and molecular markers of drug resistance. Each approach has its implications of use as well as its advantages and drawbacks...

Plasmodium genome in blood donors at risk for malaria after several years of residence in Italy [Transfusion] — (English)
This study examines Plasmodium infection in at-risk blood donors in Northern Italy...