19.05.2014

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Announcements / Press Releases

The 26th RBM Board Meeting [RBM] — (English)
Representatives of all RBM constituencies have come to Geneva to participate in informational and decision-making sessions that will help the RBM Board give direction to the Partnership's work over the year and beyond...
More info on RBM Board
26th RBM Board Decision Points
View market place slide show on the RBM Flickr
RBM Board slide show
Ministerial session slide show



Endemic Countries RBM Board Members Meet In Geneva to Plan for a Strategy Development and Positioning Meeting for Endemic Countries Health Ministers in Victoria Falls, Zimbabwe on 06 July 2014 [SARN press release] — (English)
Endemic Countries Board Members made up of Health Ministers from Kenya, Sierra Leone, Corte de Ivory, Zimbabwe, Gabon and representatives from India and Thailand met during the RBM Ministerial Session lunch to discuss mechanisms for strengthening endemic countries participation/representation in Board Meetings, strategies for filling the gap created by the shrinking RBM resources envelop, reaching consensus and mounting a common position on decisions of the Board in preparation for the 27th Board Meeting and strengthening collaboration in preparation for the post-2015 agenda...

WHO releases new tool to track efficacy of antimalarial drugs [WHO/GMP] — (English)
WHO has released two interactive maps providing a visual overview of the status of antimalarial drug efficacy for P. falciparum and P. vivax malaria. The maps chart the results of hundreds of therapeutic efficacy studies conducted around the world between 2005 and 2013. The studies make up the largest collection of antimalarial drug efficacy studies ever reviewed and standardized for analysis, forming the basis of WHO’s global surveillance system to monitor the emergence of antimalarial drug resistance...

Sixty-seventh World Health Assembly opened in Geneva [WHO] — (English)
WHO’s annual assembly opened in Geneva today, as a new global survey reveals that WHO is one of the world’s 2 most highly rated international organizations...

Malaria kills 1,500 children per day, but progress is being made [Catholic online] — (English)
Mosquitos get a bad rap because they are inadvertent killers. No mosquito wants to kill its host, instead she just wants a quick, painless meal of blood to sustain herself and her children growing as eggs inside...

Malaria Atlas Project: SEEG Data Archive Manager [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 05.06.2014...

Malaria Atlas Project: Postdoctoral Statistical Epidemiologist [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 21.05.2014...

Malaria Atlas Project: Research Assistant [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 21.05.2014...

Malaria Atlas Project: Senior Postdoctoral Modeller [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 21.05.2014...

Malaria Atlas Project: Senior Computational Statistician: Spatial Models [MAP, Department of Zoology, University of Oxford] — (English)
Application deadline: 28.05.2014...

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Articles requiring subscription or registration

In for the long haul: 20 years of malaria surveillance [The Lancet Infectious Diseases, doi:10.1016/S1473-3099(14)70742-X] — (English)
The past 20 years have seen many changes in malaria control. In most countries where malaria is endemic, first-line treatment has switched several times as drug resistance has developed, moving from chloroquine through to artemisinin-based combination therapies. In the past decade, thanks to increased funding through the Global Fund to Fight AIDS, Tuberculosis and Malaria, coverage of long-lasting insecticide-treated nets (LLINs) has massively expanded...

A next generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion [Mol Ther. doi: 10.1038/mt.2014.85] — (English)
Using an improved humanized mouse model transplanted with human hepatocytes and human red blood cells, we show that despite a high dose sporozoite challenge, Pf p52-/p36-/sap1- GAP did not transition to blood stage infection and appeared to be completely attenuated...

Relative Undernourishment and Food Insecurity Associations with Plasmodium falciparum Among Batwa Pygmies in Uganda: Evidence from a Cross-Sectional Survey [Am J Trop Med Hyg 2014 13-0422] — (English)
We investigated associations between Plasmodium falciparum infection, nutrition, and food security in a cross-sectional survey of 365 Batwa pygmies in Kanungu District, Uganda in January of 2013...

The Practice of Jhum Cultivation and Its Relationship to Plasmodium falciparum Infection in the Chittagong Hill Districts of Bangladesh [Am J Trop Med Hyg 2014 13-0592] — (English)
We conducted qualitative interviews with jhum cultivators and surveillance workers to describe jhum cultivation and used demographic and malaria surveillance in two study unions from May of 2010 to August of 2012 to better understand the relationship between jhum cultivation and malaria infection...

Site-specific genetic engineering of the Anopheles gambiae Y chromosome [PNAS doi: 10.1073/pnas.1404996111] — (English)
Here, we characterize a transgenic strain of this mosquito species, obtained by transposon-mediated integration of a transgene construct onto the Y chromosome...

Comparison of artesunate and quinine in the treatment of severe Plasmodium falciparum malaria at Kassala hospital, Sudan [JIDC] — (English)
rtesunate is more effective than quinine, in term of parasite and fever clearance time, in the treatment of P. falciparum malaria in eastern Sudan. The study found no difference between artesunate and quinine in coma resolution time...

After 2015: infectious diseases in a new era of health and development [Phil. Trans. R. Soc. B 19 June 2014 vol. 369 no. 1645 20130426] — (English)
By scanning the wider horizon now, infectious disease specialists have the chance to shape the post-2015 era of health and development...

The role of vector control in stopping the transmission of malaria: threats and opportunities [Phil. Trans. R. Soc. B 19 June 2014 vol. 369 no. 1645 20130431] — (English)
Careful management of the resistance situation in the interim will be needed if current gains in malaria control are not to be reversed...

Evaluation of wondfo rapid diagnostic kit (Pf-HRP2/PAN-pLDH) for diagnosis of malaria by using nano-gold immunochromatographic assay [Acta Parasitologica June 2014, Volume 59, Issue 2, pp 267-271] — (English)
These results indicate that Wondfo rapid diagnostic assay may be useful for detecting P. falciparum and non-P. falciparum (especially P.v.) in patient specimen...

Clinico-pathological studies of Plasmodium falciparum and Plasmodium vivax — malaria in India and Saudi Arabia [Acta Parasitologica June 2014, Volume 59, Issue 2, pp 206-212] — (English)
In this study, cases of thrombocytopenia and haemoglobinemia were more prominent in subjects infected with Plasmodium falciparum (Welch, 1897) than those with Plasmodium vivax (Grassi et Feletti, 1890)...

Correlates of protective immunity following whole sporozoite vaccination against malaria [Immunologic Research May 2014] — (English)
Together, rodent and human vaccination studies with attenuated WSV may lead to an understanding of the correlates of protective immunity against malarial disease, and the development of new, highly efficacious vaccines...

Tetraoxane-Pyrimidine Nitrile Hybrids as Dual Stage Antimalarials [J. Med. Chem., DOI: 10.1021/jm5004528] — (English)
All tested compounds combined good blood stage activity with significant effects on liver stage parasitemia, a most welcome feature for any new class of antimalarial drug...

Immune response profile and development of pathology during Plasmodium berghei Anka infection: the role of the aryl hydrocarbon receptor (AhR) [IAI.01733-14] — (English)
These data suggest that AhR mediated control of SOCS3 expression is probably involved in the phenotype seen in infected AhR-KO mice. This is, to our knowledge, the first demonstration of a role for AhR in the pathogenesis of malaria...

Association of heme oxygenase 1 with the restoration of liver function after damage in murine malaria by Plasmodium yoelii [IAI.01598-14] — (English)
We propose that selective induction of HO-1 in liver would be beneficial for the restoration of liver function after parasite clearance...

Risk of malaria among febrile patients: retrospective analysis of a hospital-based study in an endemic area of northeast India [Int. Health (2014) doi: 10.1093/inthealth/ihu020] — (English)
The study emphasises the need to strengthen and improve the treatment facilities for malaria in government hospitals, and to create more awareness among people regarding early treatment, especially in the rural periphery villages of the endemic areas...

Malaria prevention in the pregnant traveller: A review [Travel Med Infect Dis. doi: 10.1016/j.tmaid] — (English)
For pregnant women, mefloquine appears to be the drug of choice for prophylaxis and stand by-therapy if no contraindications exist – despite recent renewed warnings related to prolonged side effects. In areas with high resistance against mefloquine or in women with contraindications to mefloquine, atovaquone–proguanil or artemether–lumefantrine should be considered as an option for stand-by emergency therapy. Nevertheless, evidence on the safety of anti-malarials especially during the first trimester is still insufficient...