14.07.2014

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Announcements / Press Releases

Central African Sub Regional Network looks for evidence based data to improve malaria programme decision making [RBM CARN] — (English)
Anthropologists, socio-economists, parasitologists, entomologists, clinicians from Universities and Research institutions of DRC, Congo, Chad, Gabon, Cameroon, country NMCPs and WHO national programme officers and inter-country teams, met with National Malaria Control Programme managers in Doula, Cameroon for the first time, to look at how better to inform malaria programme design with vital evidence collected by research institutions. Together they drew up a declaration of collaboration to strengthen links between researchers and programme planners. [in French]...

Latest report in RBM’s Progress & Impact Series launches at the United Nations Headquarters in New York [RBM press release ] — (English)
Against the background of the annual High-Level Segment of the United Nations Economic and Social Council (ECOSOC) in New York, health and development leaders from the UN and diplomatic communities launched a new report, titled "The Contribution of Malaria Control to Maternal and Newborn Health." [in French]...

The contribution of malaria control to maternal and newborn health [RBM] — (English)
Prevention of malaria in pregnancy is a key component of malaria control and an important contributor to maternal and child health. National policies and effective delivery of available preventive measures in the antenatal setting will directly contribute to achieving the Millennium Development Goals (MDGs) [in French]...

Web consultation launched on draft global malaria strategy [WHO] — (English)
Following support from Member States at the 66th World Health Assembly to develop a draft global malaria strategy for the post-2015 period, seven regional consultations were held to gather input from more than 400 experts representing national malaria programmes, ministries of health, research organizations and implementing partners...

The 'yin and yang' of malaria parasite development [The University of Nottingham] — (English)
Dr Rita Tewari in the School of Life Sciences at The University of Nottingham has completed what she describes as a ‘Herculean study’ into the roles played by the 30 protein phosphatases and 72 kinases – enzymes that act as the ‘yin and yang’ switches for proteins – as the malaria parasite develops in the body and then in the mosquito gut...

MMV Director, Formulation Project Lead [MMV] — (English)
Reporting to the Head of Product Development, the Director will be responsible for successfully leading the strategy and implementation of technical development activities with the purpose of delivering new affordable antimalarial drugs in accordance with MMV’s mission...
Application deadline: 3.08.2014...


Senior Computational Statistician: Spatial Model [Malaria Atlas Project] — (English)
The Department of Zoology at the University of Oxford is looking for an experienced statistical modeller with skills in conceiving, implementing, and testing bespoke spatial statistical models on a 2-year fixed-term contract...
Application deadline: 16.07.2014...


Malaria Atlas Project: SEEG Data Archive Manager [Malaria Atlas Project] — (English)
The Data Archive Manager will be responsible for the management of the group’s spatiotemporal data archives, supporting this area of highly technical and interdisciplinary science...
Application deadline: 16.07.2014...


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13.07.2014

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9.07.2014

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Articles requiring subscription or registration

Genome-wide Functional Analysis of Plasmodium Protein Phosphatases Reveals Key Regulators of Parasite Development and Differentiation [Cell Host and icrobes Volume 16, Issue 1, 9 July 2014, Pages 128–140] — (English)
These findings provide systematic functional analyses of PPs in Plasmodium, identify how phosphatases regulate parasite development and differentiation, and can inform the identification of drug targets for malaria...

Plasmodium falciparum transmission stages accumulate in the human bone marrow [Sci Transl Med 9 July 2014: Vol. 6, Issue 244, p. 244re5] — (English)
We performed a systematic organ survey in pediatric cases of fatal malaria to characterize the spatial dynamics of gametocyte development in the human host...

Malaria vector control at crossroads: public health entomology and the drive to elimination [Trans R Soc Trop Med Hyg (2014) doi: 10.1093/trstmh/tru101] — (English)
Skilled cadres are needed to manage insecticide resistance, to maintain coverage with current interventions, to develop new paradigms for tackling ‘residual’ transmission, and to target interventions as transmission becomes increasingly heterogeneous. Recognising this human resource crisis, in September 2013, WHO Global Malaria Programme issued guidance for capacity building in entomology and vector control, including recommendations for countries and implementing partners...

Deletion of C-reactive protein ameliorates experimental cerebral malaria? [Trans R Soc Trop Med Hyg (2014) doi: 10.1093/trstmh/tru098] — (English)
Using CRP-transgenic and CRP-deficient mice we compared the onset and severity of experimental cerebral malaria (ECM) induced by Plasmodium berghei ANKA (PbA)...

Exploring the Important Correlates of Maternal Education and Childhood Malaria Infections [Am J Trop Med Hyg 2014 13-0713] — (English)
This study explored the interaction between maternal education and childhood malaria infections...

Cluster Randomized Trial of Text Message Reminders to Retail Staff in Tanzanian Drug Shops Dispensing Artemether-Lumefantrine: Effect on Dispenser Knowledge and Patient Adherence [Am J Trop Med Hyg 2014 14-0126] — (English)
In this cluster randomized trial in drug shops in Tanzania, 42 of 82 selected shops were randomized to receive text message reminders about what advice to provide when dispensing artemether-lumefantrine (AL)...

New insight in the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium - a new type of antimalarial [AAC.00040-14] — (English)
Here, we provide new insight on the choline analogue albitiazolium, which is currently clinically tested against severe malaria...

A randomized comparison of the efficacy and tolerability of three artemisinin-based combination treatments for children with acute falciparum malaria in The Democratic Republic of Congo [AAC.02682-14] — (English)
An open label, randomized controlled trial was carried out in 2011-12 in the Democratic Republic of Congo to test the efficacy, safety and tolerability of the artemisinin-based combination treatments dihydroartemisinin-piperaquine, amodiaquine-artesunate and artemether-lumefantrine...

First record of the Asian malaria vector Anopheles stephensi and its possible role in the resurgence of malaria in Djibouti, Horn of Africa [Acta Tropica] — (English)
Rapid interruption of the urban malaria transmission cycle, based on integrated vector surveillance and control programs aimed at the complete eradication of A. stephensi from the African continent, is strongly recommended...

A Serine Protease Homolog Negatively Regulates TEP1 Consumption in Systemic Infections of the Malaria Vector Anopheles gambiae [J Innate Immun (DOI:10.1159/000363296)] — (English)
Here, we show that CLIPA2, a clip domain serine protease homolog of Anopheles gambiae, regulates the consumption of the mosquito complement-like protein TEP1 during systemic bacterial infections...